Research Paper Volume 15, Issue 14 pp 6894—6904

Figure 4. CIP2A mediates cytotoxicity of celastrol by triggering MCL-1 Degradation. (A, B) AGS and BCG-823 cells were transfected with siNC or siCIP2A for 48 h, the expression of CIP2A, BCL-2, BCL-x_L and MCL-1 were detected by real-time PCR (A) and western blotting (B) assays.