Research Paper Volume 15, Issue 15 pp 7408—7423

Senescence-related gene c-Myc affects bladder cancer cell senescence by interacting with HSP90B1 to regulate cisplatin sensitivity

class="figure-viewer-img"

Figure 2. Prognostic model of senescence-related genes. (A) Partial likelihood deviance versus log (λ) was drawn using LASSO Cox regression model. (B) Coefficients of selected features are shown by lambda parameter. (C) Distribution of risk score, survival status, and the expression of 5 prognostic senescence-related genes in bladder urothelial carcinoma (BLCA). (D, E), Overall survival curves for BLCA patients in the high-/low-risk group and the ROC curve of measuring the predictive value.