Research Paper Volume 15, Issue 13 pp 6264—6291
Identification of natural killer cell-related characteristics to predict the clinical prognosis and immune microenvironment of patients with low-grade glioma
Figure 2. Significantly activated pathways in different molecular subtypes. (A) GSEA analysis results in the TCGA-LGG cohort. (B) Variation in the scores of 10 tumor abnormality-related pathways in various TCGA-LGG molecular subtypes in the **P < 0.01; ***P < 0.001; ****P < 0.0001. Abbreviations: ns: no significance; NES: normalized enrichment scores; ssGSEA: single-sample GSEA; GSEA: gene set enrichment analysis; TCGA: The Cancer Genome Atlas; LGG: low-grade glioma; TP53: tumor protein p53; PI3K: phosphatidylinositol 3-kinase; NRF1: nuclear respiratory factor-1; TGF-β: transforming growth factor-β.