Research Paper Volume 15, Issue 12 pp 5854—5872
iPSC-derived exosomes promote angiogenesis in naturally aged mice
Figure 8. Comparison of serum exosomal proteins between untreated old mice and old mice pre-injected with iPSC-exosomes, and between untreated young mice and young mice pre-injected with iPSC-exosomes groups. (A, B) GO functional annotation of the up- and the down-regulated exosomal proteins in old mice pre-injected with iPSC-exosomes, respectively. (C, D) KEGG pathway enrichment analysis of up- and down-regulated exosomal proteins in old mice pre-injected with iPSC-exosomes, respectively. (E, F) GO functional annotation of the up- and the down-regulated exosomal proteins in young mice pre-injected with iPSC-exosomes group, respectively. (G, H) KEGG pathway enrichment analysis of up- and down-regulated exosomal proteins of young mice pre-injected with iPSC-exosomes group. BP, biological process; MF, molecular function; CC, cellular component.