Research Paper Volume 15, Issue 12 pp 5854—5872

iPSC-derived exosomes promote angiogenesis in naturally aged mice

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Figure 5. Treatment with iPSC-derived exosomes increased total antioxidant capacity (TAOC) in organs of old mice. The TAOC of heart, liver, spleen, lung, kidney, brain, skin, and muscle were measured using ABTS kit. Young: untreated young mice; young + exo: young mice pre-treated with iPSC-derived exosomes via tail vein injection; Old: untreated old mice; Old + exo: old mice pre-treated with iPSC-derived exosomes via tail vein injection. TAOC, the total antioxidant capacity; iPSCs, induced pluripotent stem cells; exo, exosomes.