Review Volume 15, Issue 13 pp 6577—6619
Crosstalk between m6A and coding/non-coding RNA in cancer and detection methods of m6A modification residues
Figure 5. Interplays of m6A and lncRNAs. m6A can modulate the stability, degradation, or accumulation of lncRNAs to regulate cancer initiation, progression, and therapy. Conversely, lncRNAs can serve as ceRNAs to regulate m6A regulators via sponging miRNAs or interact directly with m6A regulators to facilitate or inhibit cancer. Abbreviations: BC: breast cancer; HCC: hepatocellular carcinoma; PCA: prostate cancer; LC: lung cancer; GC: gastric cancer; PC: pancreatic cancer; OS: osteosarcoma; CRC: colorectal cancer; RCC: renal cell carcinoma; PTC: papillary thyroid cancer; ESCC: esophageal squamous cell carcinoma; GBM: glioblastoma.