Review Volume 15, Issue 13 pp 6577—6619
Crosstalk between m6A and coding/non-coding RNA in cancer and detection methods of m6A modification residues
Figure 3. m6A regulates coding RNAs in cancers. Generally, m6A promotes cancer via the stabilization or translation of oncogenes and the degradation of tumor suppressor genes. Adversely, m6A suppresses cancer via the stabilization or translation of tumor suppressor genes, the degradation of the oncogene. Abbreviations: GBM: glioblastoma; GC: gastric cancer; HB: hepatoblastoma; OS: osteosarcoma; BCA: bladder cancer; LCA: lung cancer; HCC: hepatocellular cancer; PCA: prostate cancer; CRC: colorectal cancer; BC: breast cancer; LUSC: lung squamous cell carcinoma; MEL: melanoma; OM: ocular melanoma; RCC: renal cell carcinoma; EC: endometrial carcinoma.