Review Volume 15, Issue 13 pp 6577—6619

Crosstalk between m6A and coding/non-coding RNA in cancer and detection methods of m6A modification residues

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Figure 2. Overview of m6A-mediated RNA metabolism. “Writers” install m6A on coding RNAs and non-coding RNAs, whereas m6A can be reversibly removed by “Erasers”. Diverse m6A “Readers” determine the fate of m6A-modified RNAs involved in the structural switch, splicing, translocation, translation, and decay. MTC, methyltransferase complex.