Research Paper Volume 15, Issue 12 pp 5611—5649
Identifying the role of NUDCD1 in human tumors from clinical and molecular mechanisms: a study based on comprehensive bioinformatics and experimental validation
Figure 4. Genetic and epigenetic features of NUDCD1 in different tumors. (A) Alteration frequencies of NUDCD1 across different tumors from cBioPortal. (B) General mutation counts of NUDCD1 in various TCGA cancer types from cBioPortal. (C) Disease free survival (DFS) and progression free survival (PFS) between mutant and WT NUDCD1 in human cancers. (D) Mutation types and sites of NUDCD1 from cBioPortal. (E) SNV (Single Nucleotide Variation) of NUDCD1 in human cancers. The heatmap summarizes the frequency of deleterious mutations (data from GSCA). (F) Survival differences between mutant and WT NUDCD1 in human cancers (data from GSCA). (G) CNV (Copy Number Variation) of NUDCD1 in each cancer type. A global profile for heterozygous/homozygous CNV of NUDCD1 in each cancer (data from GSCA). (H) Survival differences between CNV and WT NUDCD1 in each cancer type (data from GSCA).