Priority Research Paper Volume 1, Issue 12 pp 979—987
Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1
Figure 1. Continuous administration of NAC affects age-dependent changes in body weight. Total body weight of male (A) WT and (B) Bmal1-/- mice, closed circles - control mice raised on regular water; open circles - mice raised on water supplemented with 40mM of NAC. (C) Relative water consumption by WT mice receiving either regular (closed bar) or NAC-supplemented (open bar) water. (D) Age-dependent changes in relative body weight in Bmal1-/- mice measured at each time point as the percentage of the body weight of WT mice of the same group.