Research Paper Volume 2, Issue 1 pp 28—42

Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

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Figure 3. Polarized secretion of PEDF and VEGF in differentiated human RPE cells. Human polarized RPE cells on transwells isolated from 3 different donors preferentially secreted PEDF (A) to the apical side of the tissue and VEGF-A (B) to the basolateral side. The bars represent average of 2 determinations for each donor with variation in each sample <5%.