Research Paper Volume 1, Issue 6 pp 529—541

dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction

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Figure 1. Low calorie diet is associated with increased spontaneous physical activity of Drosophila. Sum of 24-hour spontaneous physical activity of Canton-S male (A) and female (B) flies on a low (0.5X) and a high (1.5X) calorie food based on collected data for days 4 and 9. Both male and female flies on 0.5X food have increased spontaneous physical activity compared to the flies on l.5X food. The mobility was based on the mean mobility of 3 vials with 10 male or 10 female flies each, and expressed as mean total activity per vial during 24 hours +/- SEM. (C) Mean total 24 hours spontaneous activity of male and female CS flies on 0.5X and 1.5X food at age 4 and 9 expressed per vial. Statistical significance was determined by using two-tailed Student's t-test for independent samples.