Research Paper Volume 1, Issue 2 pp 266—274

Figure 1. Linkage disequilibrium structure and haplo-typic architecture in CD36.. (A) Haploview plot defining haplotype block structure of the CD36 region. Linkage disequilibrium (LD) was measured using data from all subjects in the present study. The haplotype blocks were determined using the criteria described by Gabriel et al. [33]. The physical position of each SNP is presented in the upper diagram. Each box provides estimated statistics of the coefficient of determination (r²), with darker shades representing stronger LD. (B) Haplotypes in the haplotype blocks across the CD36 region. There are three haplotype blocks across the region. The haplotype frequencies are shown to the right of each haplotype. Only haplotypes having a frequency greater than 1% are shown. The SNP numbers across the top of the haplotypes correspond to those in the Haploview plot. A multiallelic D′ statistic, which indicates the level of recombination between two blocks, is shown in the crossing area. Connections from one block to the next were shown for haplotypes of greater than 10% frequency with thick lines and greater than 1% frequency with thin lines.