Research Paper Volume 16, Issue 4 pp 3837—3855

Dickkopf-1 is an immune infiltration-related prognostic biomarker of head and neck squamous cell carcinoma

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Figure 4. Correlation between DKK1 expression and immune cell infiltration levels in human cancers, based on information in the TIMER and TISIDB databases. (A) DKK1 expression levels in HNSCC tissues correlated negatively with the levels of B cell and CD8+ T cell infiltration into tumors. (B) Relations between DKK1 expression and the levels of 28 types of TILs in human heterogeneous cancers. (C) The top six TILs displayed significant differences in Spearman correlation coefficients with DKK1-expression differences in HNSCC.