Research Paper Volume 16, Issue 3 pp 2953—2977
Overexpression of SPP1 is a prognostic indicator of immune infiltration in lung adenocarcinoma
Figure 5. Comprehensive analysis of the functional role of SPP1 in LUAD. (A) Analysis of individual cells revealed multiple influence of SPP1, including cell metastasis, epithelial-to-mesenchymal transition, angiogenesis, DNA damage, cell dormancy, cancer cell invasion, and cellular differentiation. (B) Functional status profile showcasing the diverse activity of function states of LUAD cells. (C) Metastasis of lung cancer associated with SPP1 expression. (D) HALLMARK term analysis revealed in 34 positively correlated groups. **p<0.01, ***p<0.001.