Research Paper Volume 16, Issue 3 pp 2908—2933

Anoikis-related gene signature is associated with immune infiltration and predicts the prognosis of non-small cell lung cancer

class="figure-viewer-img"

Figure 5. Patients with higher ARGRS exhibit low immune infiltration. (A) The correlation between the fraction of T cells and ARGRS levels at the single-cell level. X-axis: the fraction of T cells of each NSCLC patient. Y-axis: the median levels of ARGRS of each NSCLC patient. (B) Boxplot showing the levels of ImmuneScore (left) and TumorPurity (right) between the ARGRS-high and low groups in the TCGA NSCLC cohort. (C) GO and KEGG analyses of genes up-regulated in the ARGRS-high and low groups in the TCGA NSCLC cohort. (D) Heatmap showing the levels of immunological markers between ARGRS-high and low groups in the TCGA NSCLC cohort. (E, F) Comparison of immunological signatures between ARGRS-high and low groups in the TCGA NSCLC cohort.