Research Paper Volume 16, Issue 2 pp 1581—1604

Identification of a basement membrane gene signature for predicting prognosis and estimating the tumor immune microenvironment in prostate cancer

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Figure 2. 120 genes were identified as DE-BMGs in PCa. (A) Venn diagram showing the acquisition of DE-BMGs in TCGA-PRAD dataset. (B) Volcano map showing 120 DE-BMGs of TCGA-PRAD dataset. Red indicates high expression, blue indicates low expression, and gray indicates no statistically significant difference. (C) Heat map of DE-BMGs in PCa (n = 423) and normal prostate tissue (n = 52), where red represents positive correlation and green represents negative correlation. (D) Bubble graph of the top 30 terms of DE-BMGs by GO analysis. (E) Bubble chart of the top 20 terms of DE-BMGs in KEGG enrichment analysis.