Research Paper Volume 15, Issue 24 pp 15183—15195
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA
Figure 5. DMC-HA inhibited TGF-β1 induced EMT in vivo. (A) Immunohistochemical (IHC) staining was performed to evaluate the expression of MMP-2, MMP-9, N-cadherin, and Vimentin in tumor tissues treated with DMC-HA and/or TGF-β1. (B) Western blot analysis was carried out to examine the expression levels of MMP-2, MMP-9, N-cadherin, and Vimentin in tumor tissues treated with DMC-HA and/or TGF-β1.