Research Paper Volume 15, Issue 24 pp 15084—15113
Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis
Figure 1. The alteration of copper metabolism in HCC. (A) The box plot showing the enrichment level of 14 copper metabolism in tumor and corresponding normal tissues from GSE14520 dataset. (B) The box plot showing the enrichment level of 14 copper metabolism in tumor, cirrhotic and normal livers from GSE25097 dataset. (C, D) The box plot showing the expression of copper ion import (C) or detoxification of copper ion (D) related genes in tumor and normal livers from the GSE14520 datasets. (E) The molecular function analysis of 134 copper metabolism-related genes in the GlueGo plug-in of the Cytoscape software. (F) KEGG analysis of 134 copper metabolism-related genes. P-values were shown as *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.