Research Paper Volume 15, Issue 19 pp 10705—10731
Targeting circular RNA-Glra2 alleviates retinal neurodegeneration induced by ocular hypertension
Figure 3. Bioinformatics analysis of parental genes of circRNAs by GO enrichment analysis and KEGG pathway analysis. (A) Gene ontology (GO) enrichment analysis included cellular components (CC), molecular functions (MF), and biological processes (BP). The functions of parental genes of the dysregulated circRNAs during retinal neurodegeneration were predicted by GO enrichment analysis. Fold enrichment analysis showed the regulation extent of the predicted functions compared with normal controls. (B) Bubble plot displayed the result of KEGG pathway analysis, showing the Top 5 signaling pathways predicted by parental genes of the dysregulated circRNAs during retinal neurodegeneration.