Research Paper Volume 15, Issue 16 pp 8275—8297

Integrative analysis links autophagy to intrauterine adhesion and establishes autophagy-related circRNA-miRNA-mRNA regulatory network

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Figure 8. (A) B-ultrasound examination, hysteroscopy, Hematoxylin-Eosin Staining of intrauterine adhesion and normal uterine cavity. Validation of 3 ARDECs and 4 ARDEGs expression of RT-PCR. Relative expression level of (B) hsa-circ-0047301, (C) hsa-circ-0032438, (D) hsacirc-0047959 were obviously upregulated. Relative expression level of (E) hsa-miR-320c showed no significant statistical differences. Relative expression level of (F) hsa-miR-345-5p, (G) hsa-miR-449a and (H) hsa-miR-449c-5p were downregulated in IUA tissue. Data are presented as mean ± SD. *P < 0.05 compared to the normal tissues.