Research Paper Volume 15, Issue 15 pp 7673—7688
Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression
Figure 1. Ferroptosis induced pathological changes in DM rats. The mRNA expression of ferroptosis related indicators of renal tissues (A–D). Immunohistochemical staining (E, 200× magnification) and semi-quantification analyses (F) of Col-I and Col-III in renal tissues of each group. The concentration of oxidant related indexes in renal tissues was measured (G–J). *P < 0.05, **P < 0.01 vs. normal group, #P < 0.05, ##P < 0.01 vs. model group.