Active components and molecular mechanisms of Sagacious Confucius’ Pillow Elixir to treat cognitive impairment based on systems pharmacology

Zhitao Hou; Xinyu Yang; Ling Jiang; Liying Song; Yang Li; Dongdong Li; Yanning Che; Xiuling Zhang; Zhongren Sun; Hongcai Shang; Jing Chen

doi:doi:10.18632/aging.204912

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Research Paper Volume 15, Issue 14 pp 7278—7307

Active components and molecular mechanisms of Sagacious Confucius’ Pillow Elixir to treat cognitive impairment based on systems pharmacology

Figure 11. Cerebrospinal fluid microdialysis results for the hippocampal CA1 region in each group. (A) Chromatogram of neurotransmitters. (B) 5-HIAA levels in each group. (C) 5-HT levels in each group. The data are presented as means ± SD (n = 3). ^**P < 0.01 and ^##P < 0.01 compared with the model group; ^#P < 0.05 compared with the 2.3 g/kg or 4.6 g/kg group. Abbreviation: ns: not significant.