Research Paper Volume 15, Issue 14 pp 6894—6904
Celastrol impairs tumor growth by modulating the CIP2A-GSK3β-MCL-1 axis in gastric cancer cells
Figure 1. Celastrol induces degradation of CIP2A. (A) Chemical structure of celastrol. (B–E) AGS, BCG-823, HGC-27 and KATO-III cells were treated with celastrol at indicated times and concentrations, the expression of CIP2A was detected by mRNA (right or down) and western blotting (left or up) assays.