Research Paper Volume 15, Issue 12 pp 5734—5750

Figure 3. SNHG3 affects BC cell growth and metastasis in vitro. (A) MDA-MB-231 and BT549 cells transfected with SNHG3 siRNAs were seeded into 6-well plates. The number of colonies was counted on the 14th day after seeding. (B) MDA-MB-231 and BT549 cells transfected with the SNHG3 siRNAs were subjected to the CCK-8 assay. (C) EdU assays were used to determine the cell proliferation ability of SNHG3 siRNAs transfected cells. (D) Flow cytometric cell cycle distribution assays to detect the proportion of BC cells in the G1, S, and G2/M phases after the transfection of SNHG3 siRNAs. (E) Transwell assays were used to determine the invasion and migration abilities of SNHG3 siRNAs transfected cells.