Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents

Vladimir N. Anisimov; Maxim V. Egorov; Marina S. Krasilshchikova; Konstantin G. Lyamzaev; Vasily N. Manskikh; Mikhail P. Moshkin; Evgeny A. Novikov; Irina G. Popovich; Konstantin A. Rogovin; Irina G. Shabalina; Olga N. Shekarova; Maxim V. Skulachev; Tatiana V. Titova; Vladimir A. Vygodin; Mikhail Yu. Vyssokikh; Maria N. Yurova; Mark A. Zabezhinsky; Vladimir P. Skulachev

doi:doi:10.18632/aging.100404

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Research Paper Volume 3, Issue 11 pp 1110—1119

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents

Figure 6. SkQ1 increases the lifespan of females of a wild rodent, the dwarf hamster Phodopus campbelli living in outdoor cages. A total of 91 animals were studied. Statistical significance p < 0.05. Two concentrations of SkQ1 (5 and 50 nmol/kg per day) were used. The data of two SkQ1 groups were combined.